Pharmacological action – bronchodilating.
Indications
adjunct to corticosteroid therapy:
– regular maintenance therapy of bronchial asthma;
– relief of attacks of bronchospasm;
– prevention of seizures caused by physical activity;
prevention and treatment of broncho-obstructive symptoms in chronic obstructive pulmonary disease (COPD).
Contraindications
hypersensitivity to formoterol or lactose;
children under 6 years old.
With caution: prescribe the drug to patients with thyrotoxicosis, pheochromocytoma, diabetes, hypertrophic obstructive cardiomyopathy, idiopathic subvalvular aortic stenosis, severe hypertension, aneurysm or other severe cardiovascular diseases (for example, coronary heart disease, tachyarrhythmia or severe heart failure).
It is necessary to prescribe the drug with caution to patients who have a prolongation of the QTc interval, as well as to patients taking drugs that can affect the duration of the QTc interval.
Special care should be taken during exacerbation of severe bronchial asthma, because. the risk of hypokalemia may be increased by hypoxia.
Use during pregnancy and lactation
Clinical experience with the drug in pregnant women is limited. In experimental animals, rejection of the implant was noted, as well as a decrease in the life expectancy of the offspring in the early postnatal period and a decrease in body weight at birth. These effects were observed at systemic exposures significantly higher than those achieved with clinical doses of the drug.
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